Do drugs work differently in men and women?editor08
Answer is YES! Gender indeed plays a big role in things like effectiveness, side-effects, efficiency of a large range of medications.
Gender plays a vital role in effects of a large range of medications. Certain antidepressants are more effective in women than men. Methotrexate clears the body 13 to 17% slower in women than in men.
Women metabolize alcohol differently as they get befuddled more rapidly than men and metabolize alcohol slower. If women respond differently than men do to alcohol, wouldn’t the same things apply for drugs? Yes!
Here are some reasons which defines my answer
Along with weight, which is one of the factors, there are several other parts of female biology that affects how a woman responds to a specific drug.
As compared to men, women have a large storage of fat. Therefore, any medication which is fat solvable mete out differently in woman. Many medications of analysis fall into this category including anti-anxiety, antidepressants and antipsychotics.
The reason is unidentified why women tend to respond better to certain antidepressants and antipsychotics. According to a study, women do enhanced than men with the selective serotonin reuptake inhibitors (SSRIs) like Zoloft, with verapamil for bipolar disorder, and also tricyclic antidepressants like Tofranil.
Digestion is yet another difference between men and women. Women produce lesser gastric acid and thus digest food slower than men. Therefore medicines like antifungal ketoconazole, that need an acidic environment, may not be very effective in women.
Effects of estrogen
Hormones also affect the ways in which drugs are metabolized in the body. Menopause and menstrual cycles make hormones of a women’s body to fluctuate. For example, estrogen can obstruct the way in which women’s body breaks down medications. As the job of liver is to filter out toxins, the body thinks medications are toxins.
When the liver doesn’t do its job of purifying properly, the concentration of the drug in the blood becomes higher. Even the medications that are filtered in the kidneys, like Anti Cancer Drugs methotrexate, clear the body to approximately 13 to 17 percent slower in women than in men.
Medications for heart also react inversely in men and women. The recommendation of low-dose aspirin, which is recommended to help the risk of cardiac arrest, has been removed for women. The reason is higher possibility for bleeding in women. For illustration, warfarin, a blood-thinning drug, which is used to prevent blood clots and strokes, is suggested in smaller doses for women.
Pain killers too act differently in men and women. Studies reveal that women taking acetaminophen (Tylenol) and non-steroidal anti-inflammatory medications, like ibuprofen, are more likely to experience high blood pressure as compared to those who didn’t take those medications.
Due to biological differences men and women act in a different way to different drug and women may be more likely than men to experience side effects of drugs. But, that doesn’t mean women should stop taking medications. Most of the time men and women are safe taking the same dosage of medication, but sometimes women are more likely to experience side effects.
Therefore it is advisable that before taking any new medication, consult your doctor or health consultant and share your history (if any) of these medications with them to avoid any possible side-effects in the future. Also you can Buy Anti-HIV Drugs Online for good qualitative Cancer Drugs .For more details you can check our site Life Cure Drugs